Unsupervised Deep Learning Methods for Biological Image Reconstruction and Enhancement


Recently, deep learning approaches have become the main research frontier for biological image reconstruction and enhancement problems thanks to their high performance, along with their ultra-fast inference times. However, due to the difficulty of obtaining matched reference data for supervised learning, there has been increasing interest in unsupervised learning approaches that do not need paired reference data. In particular, self-supervised learning and generative models have been successfully used for various biological imaging applications. In this paper, we overview these approaches from a coherent perspective in the context of classical inverse problems, and discuss their applications to biological imaging, including electron, fluorescence and deconvolution microscopy, optical diffraction tomography and functional neuroimaging.

in IEEE Signal Processing Magazine, 2021
Hyungjin Chung
Hyungjin Chung
Ph.D. student - Generative Models & Inverse Problems

My research interests include, but is not restricted to developing efficient, modular deep generative models (diffusion models), and solving real-world inverse problems (MRI, tomography, microscopy, phase retrieval, etc.) with deep generative priors.